blog - Oct 2121

New paper : Reshaping the gut microbiome in human and fiber diet improve insulin sensitivity

https://www.nature.com/articles/s41591-021-01399-2

Fecal microbial transplantation (FMT) from lean donors to patients with obesity has been associated with metabolic benefits, yet results so far have been inconsistent. In this study, they tested the application of daily fiber supplementation as an adjunct to FMT therapy to modulate cardiometabolic outcomes. They provide proof of concept for the use of a single-dose oral FMT combined with daily low-fermentable fiber supplementation to improve insulin sensitivity in patients with severe obesity and metabolic syndrome.